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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX1A
All Species:
33.64
Human Site:
S14
Identified Species:
56.92
UniProt:
Q16623
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16623
NP_004594.1
288
33023
S14
E
L
R
T
A
K
D
S
D
D
D
D
D
V
A
Chimpanzee
Pan troglodytes
XP_001146754
288
33051
S14
E
L
R
T
A
K
D
S
D
D
D
D
D
V
A
Rhesus Macaque
Macaca mulatta
NP_001028037
288
32987
S14
E
L
R
T
A
K
D
S
D
D
D
D
D
V
T
Dog
Lupus familis
XP_849756
293
33456
S19
D
S
K
Q
A
K
D
S
D
D
D
D
D
V
T
Cat
Felis silvestris
Mouse
Mus musculus
O35526
288
33036
S14
E
L
R
T
A
K
D
S
D
D
D
D
D
V
T
Rat
Rattus norvegicus
P32851
288
33049
S14
E
L
R
T
A
K
D
S
D
D
D
D
D
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233551
316
35842
S42
F
T
P
K
A
K
D
S
D
D
D
D
E
V
T
Frog
Xenopus laevis
NP_001086322
286
32704
T14
Q
L
K
A
T
R
D
T
D
D
Q
D
E
V
D
Zebra Danio
Brachydanio rerio
NP_571598
288
33347
S14
E
L
R
S
A
K
D
S
D
D
D
E
E
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
S14
A
A
L
H
A
A
Q
S
D
D
E
E
E
T
E
Honey Bee
Apis mellifera
XP_393760
291
33455
D15
A
L
V
A
A
Q
S
D
D
D
D
V
A
D
D
Nematode Worm
Caenorhab. elegans
O16000
291
33234
E15
A
L
K
A
A
Q
S
E
D
E
Q
D
D
D
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRV7
306
34701
P27
D
I
E
S
G
H
G
P
G
N
S
G
D
L
G
Baker's Yeast
Sacchar. cerevisiae
P39926
295
33715
D22
E
N
Y
E
M
Q
E
D
L
N
N
A
P
T
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
98.9
93.1
N.A.
98.2
98.6
N.A.
N.A.
85.7
67.3
82.9
N.A.
70
69.4
63.2
N.A.
Protein Similarity:
100
95.4
98.9
94.5
N.A.
98.9
99.3
N.A.
N.A.
89.8
85.7
93.4
N.A.
83.1
81.4
80
N.A.
P-Site Identity:
100
100
93.3
66.6
N.A.
93.3
93.3
N.A.
N.A.
60
40
73.3
N.A.
26.6
33.3
33.3
N.A.
P-Site Similarity:
100
100
93.3
80
N.A.
93.3
93.3
N.A.
N.A.
66.6
73.3
93.3
N.A.
46.6
40
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.2
24.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.3
47.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
0
22
79
8
0
0
0
0
0
8
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
0
0
65
15
86
79
65
65
58
15
15
% D
% Glu:
50
0
8
8
0
0
8
8
0
8
8
15
29
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
8
0
8
0
0
8
0
0
15
% G
% His:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
22
8
0
58
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
65
8
0
0
0
0
0
8
0
0
0
0
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
0
0
0
0
0
15
8
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
8
0
0
0
0
8
0
0
% P
% Gln:
8
0
0
8
0
22
8
0
0
0
15
0
0
0
0
% Q
% Arg:
0
0
43
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
15
0
0
15
65
0
0
8
0
0
0
0
% S
% Thr:
0
8
0
36
8
0
0
8
0
0
0
0
0
15
36
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
8
0
65
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _